| 01 | Biomedicine & Health· Notable Ecdysteroid signaling acts as a central switch underlying wing polyphenism in two hemipteran insectsE 87I 47N 68 | 67 | 87 | 47 | 68 | Early signal | Sep 25, 2026 |
| 02 | Quantum· Notable Aharonov–Bohm interference in a Z2 lattice gauge theory on a hybrid qubit–oscillator quantum computerE 85I 50N 66 | 67 | 85 | 50 | 66 | Early signal | Sep 25, 2026 |
| 03 | Biomedicine & Health· Notable Systematic mapping of bacteriophage gene essentiality with HIDEN-SEQE 86I 42N 70 | 66 | 86 | 42 | 70 | Early signal | Sep 25, 2026 |
| 04 | Neuroscience· Notable Dynamic attribute activation explains gaze biases in choiceE 87I 41N 69 | 66 | 87 | 41 | 69 | Early signal | Sep 25, 2026 |
| 05 | Physics· Notable Transient chaos in the self-organization of dissipative optical solitonsE 87I 51N 71 | 70 | 87 | 51 | 71 | Early signal | Sep 25, 2026 |
| 06 | Climate & Environment· Notable Public support for novel carbon removal hinges on procedural and distributive fairnessE 84I 48N 57 | 61 | 84 | 48 | 57 | Early signal | Sep 24, 2026 |
| 07 | Biomedicine & Health· Notable A transcription factor regulates development of a bacteria-housing eukaryotic cell through DNA damage mitigationE 87I 49N 78 | 73 | 87 | 49 | 78 | Early signal | Sep 24, 2026 |
| 08 | Climate & Environment· Notable Rewriting the history of the invasive spiny water flea in North AmericaE 87I 48N 69 | 68 | 87 | 48 | 69 | Early signal | Sep 24, 2026 |
| 09 | Neuroscience· Notable Lifespan single-cell transcriptomic atlas of the human prefrontal cortexE 88I 53N 76 | 73 | 88 | 53 | 76 | Early signal | Sep 23, 2026 |
| 10 | Neuroscience· Notable The lipidomic architecture of the mouse brainE 87I 49N 69 | 68 | 87 | 49 | 69 | Early signal | Sep 23, 2026 |
| 11 | Biomedicine & Health· Notable Reference genomes and fossils revise bat family phylogeny and biogeographyE 88I 54N 66 | 68 | 88 | 54 | 66 | Early signal | Sep 23, 2026 |
| 12 | Neuroscience· Notable Ultrafast venous and sagittal sinus constrictions in the brain driven by abdominal pressureE 88I 46N 74 | 70 | 88 | 46 | 74 | Early signal | Sep 23, 2026 |
| 13 | Neuroscience· Notable Single-nucleus atlas of cell-type specific genetic regulation in the human brainE 85I 56N 72 | 71 | 85 | 56 | 72 | Early signal | Sep 23, 2026 |
| 14 | Neuroscience· Notable Single-cell atlas of transcriptomic vulnerability across brain disordersE 88I 60N 71 | 72 | 88 | 60 | 71 | Early signal | Sep 23, 2026 |
| 15 | Climate & Environment· Notable The anthropogenic fingerprint on emerging infectious diseasesE 87I 51N 69 | 68 | 87 | 51 | 69 | Early signal | Sep 23, 2026 |
| 16 | Physics· Notable Gravitational torque drives multidecadal variations in length of dayE 89I 44N 74 | 70 | 89 | 44 | 74 | Early signal | Sep 23, 2026 |
| 17 | Physics· Notable Lu+ optical frequency references with accuracy verified at the 19th digitE 89I 40N 64 | 64 | 89 | 40 | 64 | Early signal | Sep 23, 2026 |
| 18 | Neuroscience· Notable Single-nucleus transcriptome-wide association study of human brain disordersE 88I 52N 72 | 70 | 88 | 52 | 72 | Early signal | Sep 23, 2026 |
| 19 | Quantum· Notable String-breaking dynamics in a quantum simulatorE 84I 51N 63 | 65 | 84 | 51 | 63 | Early signal | Sep 23, 2026 |
| 20 | Biomedicine & Health· Notable Lsp2 links early-life diet to adult translation and lifespan in DrosophilaE 87I 54N 69 | 69 | 87 | 54 | 69 | Early signal | Sep 23, 2026 |
| 21 | Climate & Environment· Notable Agricultural liming is a carbon sink in the Mississippi River BasinE 87I 50N 79 | 73 | 87 | 50 | 79 | Early signal | Sep 23, 2026 |
| 22 | Biomedicine & Health· Notable Structural diversification of phage tail fibers enables recognition of diverse type IV piliE 89I 49N 70 | 69 | 89 | 49 | 70 | Early signal | Sep 22, 2026 |
| 23 | Neuroscience· Notable System-level synchronization and subtype-specific modules govern brain-wide serotonin axon innervationE 89I 40N 76 | 70 | 89 | 40 | 76 | Early signal | Sep 22, 2026 |
| 24 | Space & Astronomy· Notable Meteoritic organic matter records primitive oxygen reservoirs of the solar systemE 89I 50N 73 | 70 | 89 | 50 | 73 | Early signal | Sep 21, 2026 |
| 25 | Other frontiers· Notable Bistability of compartmentalized autocatalytic systems at the dawn of hereditary variationE 89I 50N 69 | 69 | 89 | 50 | 69 | Early signal | Sep 21, 2026 |
| 26 | Physics· Notable Zinc isotopic evidence for an Archean initiation of deep carbon cyclingE 92I 39N 67 | 66 | 92 | 39 | 67 | Early signal | Sep 18, 2026 |
| 27 | Physics· Notable Disorder-promoted stabilityE 86I 52N 72 | 70 | 86 | 52 | 72 | Early signal | Sep 17, 2026 |
| 28 | AI & Computing· Notable Reimagining research papers as interactive and reliable AI agentsE 94I 43N 76 | 72 | 94 | 43 | 76 | Early signal | Sep 16, 2026 |
| 29 | Biomedicine & Health· Notable Developmental xenocortication using human-derived organoids in miceE 92I 46N 70 | 68 | 92 | 46 | 70 | Early signal | Sep 16, 2026 |
| 30 | Biomedicine & Health· Notable Molecular-level observation of the self-assembly of a virus-like particleE 94I 42N 74 | 70 | 94 | 42 | 74 | Early signal | Sep 16, 2026 |
| 31 | Neuroscience· Notable Intracranial recordings in humans reveal differential contributions of medial and lateral orbitofrontal cortex to approach–avoidance decision-makingE 91I 45N 66 | 66 | 91 | 45 | 66 | Early signal | Sep 15, 2026 |
| 32 | Materials & Energy· Notable Catalytic Asymmetric Spiroannulation to Access Polycyclic Spiro Enones via Transient Axial-to-Point Chirality Induction and TransferE 83I 35N 55 | 55 | 83 | 35 | 55 | Early signal | Sep 12, 2026 |
| 33 | Materials & Energy· Notable Disentangling the effect of space and electric field on photoelectrochemical water splittingE 83I 32N 63 | 60 | 83 | 32 | 63 | Early signal | Sep 12, 2026 |
| 34 | Neuroscience· Notable Identifiability of Bayesian models of perceptionE 94I 39N 65 | 64 | 94 | 39 | 65 | Early signal | Sep 11, 2026 |
| 35 | Climate & Environment· Notable Divergence between physical and emotional heat resilience in Chinese citiesE 88I 36N 65 | 62 | 88 | 36 | 65 | Early signal | Sep 11, 2026 |
| 36 | Biomedicine & Health· Notable Multicellular rosette formation guides epithelial tissue assembly in pancreatic ductal adenocarcinoma cell organoidsE 94I 36N 68 | 65 | 94 | 36 | 68 | Early signal | Sep 11, 2026 |
| 37 | Biomedicine & Health· Notable Formin-1 maintains cochlear microtubule architecture required for hearing in humans and miceE 96I 36N 69 | 66 | 96 | 36 | 69 | Early signal | Sep 11, 2026 |
| 38 | Materials & Energy· Notable Imaging the Meissner effect in lanthanum hydride using diamond quantum sensorsE 94I 37N 64 | 63 | 94 | 37 | 64 | Early signal | Sep 11, 2026 |
| 39 | Neuroscience· Notable Facial palsy reveals the sensorimotor contribution to facial-emotion recognitionE 94I 39N 66 | 64 | 94 | 39 | 66 | Early signal | Sep 11, 2026 |
| 40 | Climate & Environment· Notable Compound and heterogeneous relationships between climate extremes and global net migrationE 88I 41N 66 | 63 | 88 | 41 | 66 | Early signal | Sep 11, 2026 |
| 41 | Biomedicine & Health· Notable Cancer treatment alters mutant selection in normal esophagusE 89I 39N 71 | 66 | 89 | 39 | 71 | Early signal | Sep 11, 2026 |
| 42 | Climate & Environment· Notable Evolution of flowering phenology over 44 years of climate changeE 94I 35N 71 | 66 | 94 | 35 | 71 | Early signal | Sep 11, 2026 |
| 43 | AI & Computing· Notable A clinically-oriented foundation model for intraoperative pathologyE 89I 39N 68 | 64 | 89 | 39 | 68 | Early signal | Sep 10, 2026 |
| 44 | Biomedicine & Health· Notable Phenomic profiles and disease patterns of 1.9 million participants from Our Future HealthE 91I 41N 69 | 66 | 91 | 41 | 69 | Early signal | Sep 10, 2026 |
| 45 | Physics· Notable Discovery of an intrinsic non-Hermitian phase transition in a bulk condensed-matter systemE 94I 44N 74 | 70 | 94 | 44 | 74 | Early signal | Sep 10, 2026 |
| 46 | Biomedicine & Health· Notable TM184C is a GPCR-like regulator of intercellular exchange and autophagyE 96I 43N 71 | 68 | 96 | 43 | 71 | Early signal | Sep 9, 2026 |
| 47 | AI & Computing· Notable Plausible nonsense and deliberative reasoning: Benchmarking LLMs against human judgmentE 94I 41N 61 | 62 | 94 | 41 | 61 | Early signal | Sep 9, 2026 |
| 48 | Climate & Environment· Notable Seasonally asymmetric warming reshapes grassland stability across timescalesE 94I 36N 69 | 66 | 94 | 36 | 69 | Early signal | Sep 9, 2026 |
| 49 | Other frontiers· Notable Ancient proteins identify various Denisovan remains from Southwest ChinaE 94I 47N 64 | 66 | 94 | 47 | 64 | Early signal | Sep 9, 2026 |
| 50 | Space & Astronomy· Notable Planetary shielding and surface precipitation of solar energetic particles during BepiColombo’s close Mercury flybyE 88I 38N 70 | 65 | 88 | 38 | 70 | Early signal | Sep 8, 2026 |
| 51 | Climate & Environment· Notable Increasing risk of vapor pressure deficit exceeding critical thresholds for tree growthE 94I 36N 63 | 62 | 94 | 36 | 63 | Early signal | Sep 8, 2026 |
| 52 | Biomedicine & Health· Notable MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomographyE 88I 90N 72 | 79 | 88 | 90 | 72 | Early signal | Sep 8, 2026 |
| 53 | Biomedicine & Health· Notable Deconstruction of lysergic acid diethylamideE 94I 39N 67 | 65 | 94 | 39 | 67 | Early signal | Sep 8, 2026 |
| 54 | Climate & Environment· Notable Scale-dependent effects of species richness and asynchrony regulate the temporal stability of consumer-mediated nutrient dynamicsE 94I 37N 70 | 66 | 94 | 37 | 70 | Early signal | Sep 8, 2026 |
| 55 | Other frontiers· Notable Heel-strike mechanics reveal evolutionary trade-offs in hominin bipedalismE 94I 40N 75 | 69 | 94 | 40 | 75 | Early signal | Sep 8, 2026 |
| 56 | Materials & Energy· Notable Operando electrochemiluminescence imaging of intermediate evolution and kinetics in electrocatalytic nitrate reductionE 83I 28N 52 | 52 | 83 | 28 | 52 | Early signal | Sep 5, 2026 |
| 57 | AI & Computing· Notable Explainable deep learning improves human mental models of self-driving carsE 94I 42N 64 | 64 | 94 | 42 | 64 | Early signal | Sep 2, 2026 |
| 58 | AI & Computing· Notable Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLCE 91I 42N 61 | 61 | 91 | 42 | 61 | Early signal | Sep 1, 2026 |
| 59 | Biomedicine & Health· Notable Cohesin prevents local mixing of condensed euchromatic domains in living human cellsE 91I 54N 82 | 74 | 91 | 54 | 82 | Early signal | Sep 1, 2026 |
| 60 | Neuroscience· Notable Sexual dimorphism in the complete Drosophila male central nervous system connectomeThe first complete male fruit fly nervous system, brain and nerve cord, at synaptic resolution E 94I 47N 67 | 66 | 94 | 47 | 67 | Early signal | Sep 1, 2026 |
| 61 | Biomedicine & Health· Notable A Virtual Cell Model That Predicts How Cells React to Being PerturbedArc Institute's State transformer forecasts gene-expression responses in cell types it never trained on. E 94I 69N 70 | 73 | 94 | 69 | 70 | Early signal | Aug 31, 2026 |
| 62 | Neuroscience· Notable What one sees depends on how far the eye has movedE 84I 55N 90 | 77 | 84 | 55 | 90 | Early signal | Aug 30, 2026 |
| 63 | Materials & Energy· Notable Coupled spin-coordination self-adaptation drives efficient nitrate to ammonia conversionE 83I 26N 57 | 54 | 83 | 26 | 57 | Early signal | Aug 29, 2026 |
| 64 | Neuroscience· Notable A cortical output channel for perceptual categorizationOnly one deep-layer cortical output cell type gains categorical responses as mice learn to categorize sounds E 86I 51N 62 | 62 | 86 | 51 | 62 | Early signal | Aug 26, 2026 |
| 65 | Physics· Notable 3D bulk-resolved g-wave altermagnetic order parameter in CrSbMagnetic quantum oscillations resolve the g-wave order parameter of the altermagnet CrSb in 3D E 94I 38N 53 | 57 | 94 | 38 | 53 | Early signal | Aug 26, 2026 |
| 66 | Materials & Energy· Notable Electronic and solvent reorganization in proton-coupled electron transfer captured by ultrafast X-raysUltrafast X-rays resolve the electron, proton, and solvent steps of proton-coupled electron transfer in water E 87I 28N 67 | 59 | 87 | 28 | 67 | Early signal | Aug 26, 2026 |
| 67 | Neuroscience· Notable An axon-intrinsic loop restricts nerve regeneration through axonal protein synthesisA REG3A-to-KHSRP axonal loop brakes peripheral nerve regeneration through localized mRNA translation E 89I 0N 66 | 53 | 89 | 0 | 66 | Early signal | Aug 26, 2026 |
| 68 | Biomedicine & Health· Notable A complete diploid human genome benchmark for personalized genomicsA telomere-to-telomere HG002 benchmark covering the diploid genome's hardest regions E 96I 62N 62 | 65 | 96 | 62 | 62 | Early signal | Aug 1, 2026 |
| 69 | Quantum· Notable Helios: a 98-qubit trapped-ion machine that stays accurate as it scalesQuantinuum reaches beyond-classical circuits without giving up the field's best gate fidelity. E 89I 59N 60 | 59 | 89 | 59 | 60 | Early signal | Jun 17, 2026 |
| 70 | Neuroscience· Major Distributed control circuits across a brain-and-cord connectomeFirst adult fruit fly connectome joining brain and ventral nerve cord E 97I 62N 69 | 65 | 97 | 62 | 69 | Firming up | Jun 8, 2026 |
| 71 | Neuroscience· Notable Neuropixels Opto: combining high-resolution electrophysiology and optogeneticsNeuropixels probe fusing 960 recording sites with on-shank optogenetic light emitters E 93I 53N 65 | 59 | 93 | 53 | 65 | Early signal | Jun 1, 2026 |
| 72 | Biomedicine & Health· Major A Single Base-Editing Infusion Cuts LDL Cholesterol Up to 62%In vivo editing of the PCSK9 gene produced durable cholesterol reductions in an early-stage trial. E 97I 64N 73 | 65 | 97 | 64 | 73 | Firming up | May 25, 2026 |
| 73 | AI & Computing· Major Accelerating scientific discovery with Co-ScientistA multi-agent AI system on Gemini that generates and validates scientific hypotheses E 94I 86N 73 | 69 | 94 | 86 | 73 | Firming up | May 19, 2026 |
| 74 | Biomedicine & Health· Major Large-scale discovery, analysis and design of protein energy landscapesMass spec measures fluctuation energies for 5,778 protein domains in parallel E 96I 60N 65 | 60 | 96 | 60 | 65 | Firming up | May 13, 2026 |
| 75 | Materials & Energy· Major 4D printing of hierarchically porous carbon–supported high-entropy ceramic metamaterial for tunable microwave absorptionA 4D-printed metamaterial absorber that reshapes on heating to retune its radar-band absorption E 85I 68N 48 | 52 | 85 | 68 | 48 | Firming up | May 13, 2026 |
| 76 | Biomedicine & Health· Major Ancient DNA reveals pervasive directional selection across West EurasiaAncient-DNA time series reveal hundreds of alleles under directional selection in humans E 94I 64N 66 | 59 | 94 | 64 | 66 | Firming up | Apr 15, 2026 |
| 77 | Biomedicine & Health· Major Base-Edited Stem Cells Switch On Fetal Hemoglobin to Treat Sickle CellA precise single-letter edit reawakens protective fetal hemoglobin without cutting DNA. E 85I 65N 63 | 55 | 85 | 65 | 63 | Firming up | Apr 1, 2026 |
| 78 | Biomedicine & Health· Major Evo 2: a genome foundation model across all of lifeNine trillion base pairs of training, a megabase of context, single-nucleotide resolution. E 97I 86N 56 | 57 | 97 | 86 | 56 | Settled | Mar 4, 2026 |
| 79 | Biomedicine & Health· Major Bimagrumab plus semaglutide alone or in combination for the treatment of obesity: a randomized phase 2 trialBimagrumab plus semaglutide produced greater weight loss than either drug alone in a phase 2 trial E 94I 77N 50 | 53 | 94 | 77 | 50 | Firming up | Mar 1, 2026 |
| 80 | Climate & Environment· Notable MethaneSAT Maps the World's Oil and Gas Methane Super-EmittersA dedicated satellite resolves individual leaking sites across the planet's biggest fossil-fuel basins. E 86I 50N 51 | 46 | 86 | 50 | 51 | Firming up | Feb 26, 2026 |
| 81 | Neuroscience· Major Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s diseaseSingle-cell multiomic profiling maps hippocampal neurogenesis across ageing and Alzheimer's disease E 96I 67N 60 | 54 | 96 | 67 | 60 | Firming up | Feb 25, 2026 |
| 82 | Biomedicine & Health· Major Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBCAfter a personalized neoantigen mRNA vaccine, 11 of 14 TNBC patients stayed relapse-free for up to six years E 96I 67N 60 | 54 | 96 | 67 | 60 | Firming up | Feb 18, 2026 |
| 83 | Climate & Environment· Emerging A Cloud-Feedback Constraint That Points Climate Sensitivity HigherLinking tropical cloud change to ocean warming patterns halves the field's biggest uncertainty. E 88I 3N 57 | 39 | 88 | 3 | 57 | Firming up | Feb 2, 2026 |
| 84 | Space & Astronomy· Notable JWST Confirms a Bright Galaxy 280 Million Years After the Big BangMoM-z14 at redshift 14.44 pushes the spectroscopic frontier of cosmic dawn. E 90I 70N 40 | 45 | 90 | 70 | 40 | Firming up | Jan 30, 2026 |
| 85 | Biomedicine & Health· Major AlphaGenome Reads a Megabase of DNA at Single-Base ResolutionOne model predicts thousands of regulatory genomic tracks and tops specialist tools on variant effects. E 96I 90N 49 | 53 | 96 | 90 | 49 | Settled | Jan 28, 2026 |
| 86 | Climate & Environment· Major Pesticide residues alter taxonomic and functional biodiversity in soilsPesticide residues rank as the second strongest driver of soil biodiversity across European soils E 92I 72N 54 | 51 | 92 | 72 | 54 | Firming up | Jan 28, 2026 |
| 87 | Neuroscience· Notable The glymphatic system clears amyloid beta and tau from brain to plasma in humansNormal sleep raises plasma amyloid beta and tau versus sleep deprivation in a randomized crossover trial E 89I 72N 48 | 48 | 89 | 72 | 48 | Firming up | Jan 27, 2026 |
| 88 | Climate & Environment· Notable Permafrost Thaw and Arctic Fires Shrink the Paris Carbon BudgetAdding two feedbacks that models usually ignore cuts the room left under 1.5 C by a quarter. E 88I 48N 58 | 47 | 88 | 48 | 58 | Firming up | Jan 24, 2026 |
| 89 | Biomedicine & Health· Notable Nanoparticles hijack calvarial immune cells for CNS drug delivery and stroke therapyDrug-loaded nanoparticles hijack skull immune cells to bypass the blood-brain barrier for stroke therapy E 92I 67N 53 | 49 | 92 | 67 | 53 | Firming up | Jan 16, 2026 |
| 90 | Space & Astronomy· Notable JWST's 'Little Red Dots' Are Young Black Holes in Glowing CocoonsElectron-scattering line shapes cut estimated black-hole masses about a hundredfold. E 96I 74N 42 | 47 | 96 | 74 | 42 | Settled | Jan 14, 2026 |
| 91 | Biomedicine & Health· Notable Mapping somatosensory afferent circuitry to bone identifies neurotrophic signals required for fracture healingA single-cell map of bone-innervating sensory neurons identifies FGF9 as a driver of fracture repair E 81I 68N 54 | 48 | 81 | 68 | 54 | Firming up | Jan 8, 2026 |
| 92 | Biomedicine & Health· Notable An Immune Map of a Pig Kidney in a Living PersonHigh-dimensional profiling reveals how a gene-edited pig organ is rejected, and how it holds. E 93I 66N 49 | 47 | 93 | 66 | 49 | Firming up | Jan 1, 2026 |
| 93 | Materials & Energy· Notable Limiting phosphonic acid interlayer–perovskite reactivity to stabilize perovskite solar modulesA strongly binding phosphonic acid interlayer gives perovskite cells a T90 of nearly 3000 hours at 85°C E 81I 72N 48 | 45 | 81 | 72 | 48 | Firming up | Jan 1, 2026 |
| 94 | AI & Computing· Notable AI-enabled virtual spatial proteomics from histopathology for interpretable biomarker discovery in lung cancerAn AI model generates spatial proteomics from H&E slides to improve lung cancer prognostic accuracy E 93I 71N 48 | 47 | 93 | 71 | 48 | Firming up | Jan 1, 2026 |
| 95 | Physics· Notable EAST Tokamak Runs Stably Past the Greenwald Density LimitA Chinese fusion device holds plasma densities up to 65% above a barrier long thought to trigger disruption. E 89I 44N 50 | 43 | 89 | 44 | 50 | Firming up | Jan 1, 2026 |
| 96 | Biomedicine & Health· Major Mapping the genetic landscape across 14 psychiatric disordersFive genomic factors explain most shared genetic risk across 14 psychiatric disorders E 96I 76N 56 | 51 | 96 | 76 | 56 | Settled | Dec 10, 2025 |
| 97 | Biomedicine & Health· Major RFdiffusion2 Designs Enzymes Directly From Catalytic GeometryA generative model scaffolds enzyme active sites from functional-group positions alone, no residue order required. E 91I 75N 61 | 51 | 91 | 75 | 61 | Settled | Dec 3, 2025 |
| 98 | Biomedicine & Health· Notable Designing Zinc Enzymes from Scratch That Rival Nature's Catalytic SpeedA generative model builds active metallohydrolases straight from chemistry, no lab tinkering required. E 94I 66N 56 | 48 | 94 | 66 | 56 | Firming up | Dec 3, 2025 |
| 99 | Space & Astronomy· Notable Bennu's Grains Carry the Building Blocks of LifeReturned asteroid samples hold nucleobases, amino acids, and a first hint of tryptophan. E 94I 61N 55 | 47 | 94 | 61 | 55 | Firming up | Nov 24, 2025 |
| 100 | Biomedicine & Health· Notable A skin-permeable polymer for non-invasive transdermal insulin deliveryE 94I 67N 50 | 46 | 94 | 67 | 50 | Firming up | Nov 19, 2025 |
| 101 | Neuroscience· Notable Deep-Brain Stimulation Finds a Signal That Predicts Who Beats DepressionAn intracranial biomarker forecasts response to BNST-NAc stimulation for treatment-refractory depression. E 89I 52N 51 | 43 | 89 | 52 | 51 | Firming up | Nov 18, 2025 |
| 102 | AI & Computing· Notable AlphaProof reaches silver-medal level at the Math OlympiadAn RL agent writes machine-checkable Lean proofs for competition mathematics. E 96I 69N 55 | 48 | 96 | 69 | 55 | Firming up | Nov 12, 2025 |
| 103 | Biomedicine & Health· Notable One CRISPR Dose Cuts a Cardiovascular Risk Gene by Nearly 90%An in vivo edit of the liver ANGPTL3 gene lowered triglycerides and LDL in a phase 1 trial. E 83I 76N 47 | 44 | 83 | 76 | 47 | Settled | Nov 8, 2025 |
| 104 | Materials & Energy· Notable Homogenized chlorine distribution for >27% power conversion efficiency in perovskite solar cellsHomogenizing chlorine in perovskite films yields 27.2% certified solar-cell efficiency E 76I 85N 48 | 45 | 76 | 85 | 48 | Settled | Nov 6, 2025 |
| 105 | AI & Computing· Notable A multimodal whole-slide foundation model for pathologyA multimodal whole-slide foundation model for pathology that works without fine-tuning E 93I 82N 49 | 48 | 93 | 82 | 49 | Settled | Nov 1, 2025 |
| 106 | Quantum· Notable Google's Processor Sees Quantum Interference at the Edge of ChaosSecond-order out-of-time-order correlators stay sensitive where scrambling usually erases the dynamics. E 96I 70N 45 | 44 | 96 | 70 | 45 | Settled | Oct 22, 2025 |
| 107 | Neuroscience· Notable A Light-Powered Retinal Chip Restores Reading Vision in Advanced Macular DegenerationA subretinal photovoltaic implant plus infrared glasses gave most trial patients back central sight in a disease with no prior treatment. E 97I 69N 54 | 47 | 97 | 69 | 54 | Settled | Oct 20, 2025 |
| 108 | Climate & Environment· Emerging A Deep-Ocean Fingerprint Says the AMOC Is Already SlowingMid-depth warming in the equatorial Atlantic points to a circulation slowdown that began decades ago. E 88I 41N 47 | 38 | 88 | 41 | 47 | Firming up | Oct 17, 2025 |
| 109 | Materials & Energy· Notable Plasma-electrocatalytic synthesis of urea from air and CO2E 87I 74N 46 | 43 | 87 | 74 | 46 | Settled | Oct 3, 2025 |
| 110 | Biomedicine & Health· Notable Localized glutamine leakage drives the spatial structure of root microbial colonizationE 94I 73N 57 | 48 | 94 | 73 | 57 | Settled | Oct 2, 2025 |
| 111 | AI & Computing· Major Kolmogorov-Arnold Networks Meet ScienceA framework using Kolmogorov-Arnold networks to discover symbolic physical laws from data E 88I 94N 66 | 53 | 88 | 94 | 66 | Settled | Sep 30, 2025 |