| 01 | Climate & Environment· Notable Increased demographic turnover and isolation precede social fragmentation in Asian elephantsE 91I 44N 67 | 67 | 91 | 44 | 67 | Early signal | Nov 12, 2026 |
| 02 | Biomedicine & Health· Notable Early epidemiological and spatial assessment of the Bundibugyo virus outbreak 2026E 78I 48N 57 | 60 | 78 | 48 | 57 | Early signal | Nov 12, 2026 |
| 03 | Materials & Energy· Notable Scale-rich network-based metamaterialsStruts of many sizes let metamaterials combine direction-tunable stiffness with evenly spread deformation E 94I 43N 68 | 68 | 94 | 43 | 68 | Early signal | Nov 11, 2026 |
| 04 | Biomedicine & Health· Notable Validation of clinical and preclinical obesity across global cohortsE 89I 49N 66 | 67 | 89 | 49 | 66 | Early signal | Nov 11, 2026 |
| 05 | Biomedicine & Health· Notable Prevention of Venous Thromboembolism after Total Hip or Knee ReplacementAfter hip or knee replacement, aspirin could not be shown as effective as anticoagulants, nor they as safe as aspirin E 83I 39N 73 | 66 | 83 | 39 | 73 | Early signal | Nov 11, 2026 |
| 06 | Space & Astronomy· Notable Independent interferometric observable confirms black hole shadow in M87*E 89I 43N 63 | 64 | 89 | 43 | 63 | Early signal | Nov 11, 2026 |
| 07 | Climate & Environment· Notable Human land use drives microplastic abundance in terrestrial wildlifeTapirs and anteaters ranging closer to development and waste sites carried more microplastics in their blood E 92I 31N 64 | 62 | 92 | 31 | 64 | Early signal | Nov 11, 2026 |
| 08 | Biomedicine & Health· Notable Intismeran Autogene plus Pembrolizumab for Resected Stage IIB to IV MelanomaA personalized neoantigen therapy plus pembrolizumab prolonged recurrence-free survival in a phase 3 melanoma trial E 83I 36N 59 | 59 | 83 | 36 | 59 | Early signal | Nov 11, 2026 |
| 09 | Neuroscience· Notable Information formatting in neuronal populations predicts differential functional contributions to behaviorTwo monkey brain areas format the same signals differently, and stimulating each changed choices differently E 93I 45N 69 | 68 | 93 | 45 | 69 | Early signal | Nov 10, 2026 |
| 10 | Physics· Notable Atomically resolved superconducting gap in (La,Pr)3Ni2O7 filmsAtomic-scale spectra point to a fully opened superconducting gap in oxygen-sufficient bilayer nickelate films E 88I 51N 53 | 61 | 88 | 51 | 53 | Early signal | Nov 10, 2026 |
| 11 | AI & Computing· Notable Generating interesting scientific ideas using knowledge graphs and LLMs: Evaluations with 100 research group leadersAsked to rate over 4,400 AI-generated ideas, 100-plus group leaders called a quarter interesting E 88I 63N 72 | 73 | 88 | 63 | 72 | Early signal | Nov 9, 2026 |
| 12 | Quantum· Notable Extensive mixed-state entanglement in kinetically constrained superradianceTheory predicts that a local constraint lets a burst of superradiance entangle the emitting atoms E 88I 44N 53 | 59 | 88 | 44 | 53 | Early signal | Nov 9, 2026 |
| 13 | Quantum· Notable Controlling Rydberg atom-polariton interactions: from exceptional points to fast readoutA single atom read out by the cloud next door, after three regimes of light-matter interaction are mapped E 88I 50N 49 | 58 | 88 | 50 | 49 | Early signal | Nov 9, 2026 |
| 14 | Biomedicine & Health· Notable Efficient and accurate mixed model association tool for single-cell eQTL analysisIn 1.2 million immune cells, a single-cell model found 48.8% more eGenes than a standard pooled pipeline E 90I 53N 78 | 74 | 90 | 53 | 78 | Early signal | Nov 6, 2026 |
| 15 | Biomedicine & Health· Notable Robust fine-mapping in the presence of linkage disequilibrium mismatchA fine-mapping method holds up better than existing tools when the reference panel does not match the study E 91I 51N 70 | 70 | 91 | 51 | 70 | Early signal | Nov 6, 2026 |
| 16 | Quantum· Notable Conserved quantities enable the quantum Mpemba effect in weakly open systemsWeakly open quantum systems started in thermal states need extra conserved quantities to show the Mpemba effect E 86I 53N 52 | 60 | 86 | 53 | 52 | Early signal | Nov 6, 2026 |
| 17 | Materials & Energy· Notable Atomically resolved exciton emission from single defects in MoS2Atom-scale light maps trace a common defect glow in the semiconductor MoS2 to carbon-hydrogen complexes E 88I 44N 70 | 67 | 88 | 44 | 70 | Early signal | Nov 5, 2026 |
| 18 | AI & Computing· Notable Denoising the US Census: Succinct block hierarchical regressionA new algorithm could make 2020 Census tables more accurate without weakening their privacy protection E 89I 49N 62 | 64 | 89 | 49 | 62 | Early signal | Nov 5, 2026 |
| 19 | Physics· Notable Seafloor geodesy delineates fast megathrust relocking after the giant 2011 Tohoku earthquakeMeasurements and models indicate the fault behind the 2011 Tohoku quake is locked again, as before it struck E 78I 38N 66 | 62 | 78 | 38 | 66 | Early signal | Nov 5, 2026 |
| 20 | Physics· Notable Equivalence of pseudogap and pairing energy in a cuprate high-temperature superconductorElectron pairing sets in at the pseudogap energy in a cuprate superconductor, noise measurements show E 91I 50N 49 | 59 | 91 | 50 | 49 | Early signal | Nov 5, 2026 |
| 21 | Physics· Notable Multimodal X-ray imaging reveals hierarchical fibre mechanicsA new X-ray method maps how collagen fibrils and fibres share load inside intact rat spinal discs E 91I 47N 85 | 77 | 91 | 47 | 85 | Early signal | Nov 4, 2026 |
| 22 | AI & Computing· Notable Intrinsically motivated humans and agents in open-world explorationChildren, adults and AI agents in a Minecraft-like game seem to seek novelty first, then control E 91I 57N 71 | 71 | 91 | 57 | 71 | Early signal | Nov 4, 2026 |
| 23 | Biomedicine & Health· Notable A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneityA map of 12 glioblastomas finds their cells on one path, from development-like states to injury and low oxygen E 94I 48N 70 | 70 | 94 | 48 | 70 | Early signal | Nov 4, 2026 |
| 24 | Neuroscience· Notable Aggression experience and observation drive shared behavioural and neural changesMice that only watched fights later fought more like experienced fighters, with shared brain changes E 93I 45N 72 | 70 | 93 | 45 | 72 | Early signal | Nov 4, 2026 |
| 25 | Neuroscience· Notable Transcriptomic convergence and the female protective effect in autismSeparately knocking down 18 autism genes in lab-grown neural cells lowered many of the same other autism genes E 95I 59N 64 | 69 | 95 | 59 | 64 | Early signal | Nov 4, 2026 |
| 26 | Quantum· Notable Observation of prethermal dynamical phase transitions and resonant meltingAn atom simulator running up to 180 qubits finds quantum states that hold off thermalization E 91I 50N 64 | 67 | 91 | 50 | 64 | Early signal | Nov 4, 2026 |
| 27 | Space & Astronomy· Notable Exorcising ghosts with gravitational wavesPulsars and a neutron-star merger set a lower mass limit on the extra modes of 'ghostful' quadratic gravity E 86I 45N 68 | 66 | 86 | 45 | 68 | Early signal | Nov 4, 2026 |
| 28 | Biomedicine & Health· Notable Cancer-selective gene circuits via intrinsic ribosomal frameshiftingA gene circuit keyed to a slip in the ribosome's reading frame makes cancer cells kill themselves in mice E 81I 30N 77 | 66 | 81 | 30 | 77 | Early signal | Nov 4, 2026 |
| 29 | Materials & Energy· Notable Twist-angle-dependent quantum phase diagrams in moiré bilayer MoTe2Across fifteen devices, 3.79° to 5.76° of twist takes two atom-thin sheets to superconductivity E 91I 56N 54 | 63 | 91 | 56 | 54 | Early signal | Nov 4, 2026 |
| 30 | Space & Astronomy· Notable Modified Newtonian Dynamics and galaxy clustersAcross 106 galaxy clusters, MOND needs 4 to 10 times less mass than Newton but still some unseen matter E 86I 30N 66 | 62 | 86 | 30 | 66 | Early signal | Nov 4, 2026 |
| 31 | Physics· Notable Any-light-particle searches with ALPSII: First science resultsA laser search for axions at DESY saw none, setting a limit more than 20 times tighter than similar experiments E 88I 62N 64 | 69 | 88 | 62 | 64 | Early signal | Nov 2, 2026 |
| 32 | Neuroscience· Notable Transcranial magnetic stimulation to the dorsolateral prefrontal cortex modulates single-neuron activity in humansIn four patients, single magnetic pulses to the prefrontal cortex changed firing in 46% of recorded neurons E 91I 44N 72 | 69 | 91 | 44 | 72 | Early signal | Nov 2, 2026 |
| 33 | Biomedicine & Health· Notable TAVR in Patients with Moderate Aortic Stenosis with At-Risk FeaturesValve replacement cut combined 2-year death or heart-failure events to 16.7% from 23.9% in at-risk moderate stenosis E 83I 44N 60 | 61 | 83 | 44 | 60 | Early signal | Nov 2, 2026 |
| 34 | Biomedicine & Health· Notable Global, regional and national burden of cervical cancer in 1990–2023 with forecasts to 2050: a Global Burden of Disease studyCervical cancer killed an estimated 369,000 women in 2023, and deaths are forecast to rise by 2050 E 88I 55N 50 | 60 | 88 | 55 | 50 | Early signal | Nov 2, 2026 |
| 35 | Climate & Environment· Notable Thermal ecology drives alternate responses to rising temperatures in Caribbean anolesAnole lizards of closed Caribbean forests raised their heat tolerance by 2 °C on average in a decade E 89I 0N 69 | 56 | 89 | 0 | 69 | Early signal | Nov 2, 2026 |
| 36 | Biomedicine & Health· Notable Cross-species multiomic atlas of the primate basal gangliaE 91I 76N 67 | 74 | 91 | 76 | 67 | Early signal | Nov 1, 2026 |
| 37 | Neuroscience· Notable An astrocyte-microglia MFG-E8 axis promotes synapse engulfment in early amyloid pathologyIn mice, astrocytes in an early bulbous state release a signal microglia need to eat the synapses beside them E 90I 48N 73 | 70 | 90 | 48 | 73 | Early signal | Nov 1, 2026 |
| 38 | Neuroscience· Notable Disruption of cell-type-specific molecular programs of striatal spiny projection neurons in autismE 91I 63N 63 | 69 | 91 | 63 | 63 | Early signal | Nov 1, 2026 |
| 39 | Biomedicine & Health· Notable Efficacy and safety of efinopegdutide in adults with metabolic dysfunction-associated steatohepatitis and stage 2–3 fibrosis: a phase 2b, randomised, placebo-controlled studySteatohepatitis resolved in over half of patients analysed on each dose of a GLP-1-glucagon drug, vs 13% on placebo E 80I 36N 67 | 61 | 80 | 36 | 67 | Early signal | Nov 1, 2026 |
| 40 | Biomedicine & Health· Notable Long-term outcomes after percutaneous coronary intervention with drug-eluting stents versus coronary artery bypass grafting for left main coronary artery disease: a prospective analysis of the multicentre IRIS-MAIN registryAt 10 years, a registry found no detectable survival difference between stents and bypass surgery E 80I 38N 64 | 61 | 80 | 38 | 64 | Early signal | Nov 1, 2026 |
| 41 | Biomedicine & Health· Notable Risovalisib for PIK3CA-mutated recurrent or persistent ovarian clear cell carcinoma: a single-arm, multicentre, phase 2 trialA targeted pill shrank PIK3CA-mutated ovarian clear cell tumours in 35% of evaluable trial patients E 77I 36N 66 | 60 | 77 | 36 | 66 | Early signal | Nov 1, 2026 |
| 42 | Biomedicine & Health· Notable Activity and safety of first-line pumitamig plus nab-paclitaxel in triple-negative breast cancer: a single-arm, phase 1b/2 trialA two-target antibody with chemotherapy shrank tumours in 31 of 42 triple-negative breast cancers E 77I 34N 65 | 59 | 77 | 34 | 65 | Early signal | Nov 1, 2026 |
| 43 | Biomedicine & Health· Notable Nuclear NAD + promotes innate immune memory by inhibiting KDM5A-dependent histone demethylationE 78I 37N 79 | 67 | 78 | 37 | 79 | Early signal | Oct 30, 2026 |
| 44 | Materials & Energy· Notable One-minute frequency disturbances from unintended synchronization in cyber–physical power systemsE 88I 40N 65 | 63 | 88 | 40 | 65 | Early signal | Oct 30, 2026 |
| 45 | Biomedicine & Health· Notable Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learningE 94I 49N 70 | 70 | 94 | 49 | 70 | Early signal | Oct 29, 2026 |
| 46 | Physics· Notable Altermagnetism revealed by polarized neutrons in MnF2E 91I 64N 60 | 68 | 91 | 64 | 60 | Early signal | Oct 29, 2026 |
| 47 | Physics· Notable Chiral altermagnon in MnTeX-rays catch a one-handed spin wave in manganese telluride, just as a candidate new kind of magnet predicts E 91I 56N 66 | 68 | 91 | 56 | 66 | Early signal | Oct 29, 2026 |
| 48 | Neuroscience· Notable Intrinsic gestational timing governs human cerebellar development after preterm birthE 91I 45N 70 | 68 | 91 | 45 | 70 | Early signal | Oct 29, 2026 |
| 49 | Materials & Energy· Notable Free-standing two-dimensional metal oxides at the single-atomic-layer limitE 91I 44N 69 | 67 | 91 | 44 | 69 | Early signal | Oct 29, 2026 |
| 50 | Climate & Environment· Notable The global geography of threats to freshwater biodiversityE 92I 27N 74 | 66 | 92 | 27 | 74 | Early signal | Oct 29, 2026 |