Skip to content

AI & Computing

Latest AI Breakthroughs

Machine learning, foundation models, algorithms, and the systems that run them. Every AI & Computing result in the index, each scored against work of its own kind and ranked by Frontier Score.

Top of the field · Notable

Reimagining research papers as interactive and reliable AI agents

72/ 100

Evidence 94Impact 43Novelty 76

Read the entry

Every AI & Computing breakthrough

Ranked by live Frontier Score. Search, filter by date, or sort by any pillar.

20 breakthroughs
Sort
Since
#
01
AI & Computing· Notable
Reimagining research papers as interactive and reliable AI agents
E 94I 43N 76
72
02
AI & Computing· Notable
Large-scale semidefinite programming with graphics processing units
E 89I 51N 65
68
03
AI & Computing· Major
Accelerating scientific discovery with Co-Scientist
E 94I 87N 72
68
04
AI & Computing· Notable
A clinically-oriented foundation model for intraoperative pathology
E 89I 39N 68
64
05
AI & Computing· Notable
Explainable deep learning improves human mental models of self-driving cars
E 94I 42N 64
63
06
AI & Computing· Notable
Plausible nonsense and deliberative reasoning: Benchmarking LLMs against human judgment
E 94I 41N 61
62
07
AI & Computing· Notable
Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC
E 91I 42N 61
61
08
AI & Computing· Major
Kolmogorov-Arnold Networks Meet Science
E 88I 94N 65
53
09
AI & Computing· Notable
AlphaProof reaches silver-medal level at the Math Olympiad
E 96I 69N 55
48
10
AI & Computing· Notable
A multimodal whole-slide foundation model for pathology
E 94I 82N 49
48
11
AI & Computing· Notable
DeepSeek-R1: reasoning learned through pure reinforcement learning
E 97I 99N 44
48
12
AI & Computing· Notable
Delphi-2M: A Generative Transformer for Lifetime Disease Risk
E 91I 82N 58
48
13
AI & Computing· Notable
Data-driven de novo design of super-adhesive hydrogels
E 94I 78N 60
48
14
AI & Computing· Notable
AI-enabled virtual spatial proteomics from histopathology for interpretable biomarker discovery in lung cancer
E 93I 71N 48
47
15
AI & Computing· Notable
A Robot Performs a Full Surgical Step on Lifelike Tissue Without Human Help
E 88I 92N 49
44
16
AI & Computing· Notable
AMIE Matches Physicians at Diagnostic Conversation
E 97I 86N 46
42
17
AI & Computing· Notable
TabPFN Beats Decades of Tabular Machine Learning in Seconds
E 97I 98N 43
41
18
AI & Computing· Emerging
AlphaEvolve breaks a 56-year-old matrix-multiplication record
E 68I 50N 55
36
19
AI & Computing· Emerging
Gemini Robotics brings a foundation model into physical control
E 69I 37N 55
33
20
AI & Computing· Early
An AI Diagnostic Orchestrator Solves Hard Cases at Four Times the Physician Rate
E 69I 36N 40
29
Every score decomposes to its raw sources on the breakthrough page.scored 2026-09-30How it is computed

The rest of the frontier

The Frontier Brief

The week's frontier, scored.

Every Monday, the highest-scoring new breakthroughs in the index, each with its score and a one-line read on why it matters. What you get

One email a week. The top new breakthroughs, scored. Unsubscribe anytime.