Latest Medical Discoveries

Ancient DNA suggests Germanic may have reached Scandinavia some 800 years later than assumed

In 1.2 million immune cells, a single-cell model found 48.8% more eGenes than a standard pooled pipeline

Single-nucleus maps of 287 muscle biopsies match almost 3,500 trait signals to regulatory variants

Repeated stretches of DNA shape gene activity immune cell type by cell type, across 1,925 people

A fine-mapping method holds up better than existing tools when the reference panel does not match the study

A map of 12 glioblastomas finds their cells on one path, from development-like states to injury and low oxygen

Coral bacteria make testosterone and progesterone, and giving corals either one shifts their immune genes

State predicts how cells' gene expression responds to perturbation, and flags strong perturbations in cellular contexts where it saw none in training.

After hip or knee replacement, aspirin could not be shown as effective as anticoagulants, nor they as safe as aspirin

A gene circuit keyed to a slip in the ribosome's reading frame makes cancer cells kill themselves in mice

Confirming obesity with waist size, not just BMI, better predicts who faces higher mortality risk

In mice, deleting one immune enzyme eased organ ageing while leaving immune ageing in place