The latest scientific discoveries, scored.

Arc Institute's State transformer forecasts gene-expression responses in cell types it never trained on.

A multi-agent AI system on Gemini that generates and validates scientific hypotheses

The first complete male fruit fly nervous system, brain and nerve cord, at synaptic resolution

A telomere-to-telomere HG002 benchmark covering the diploid genome's hardest regions

In vivo editing of the PCSK9 gene produced durable cholesterol reductions in an early-stage trial.

First adult fruit fly connectome joining brain and ventral nerve cord

Only one deep-layer cortical output cell type gains categorical responses as mice learn to categorize sounds

Quantinuum reaches beyond-classical circuits without giving up the field's best gate fidelity.

Magnetic quantum oscillations resolve the g-wave order parameter of the altermagnet CrSb in 3D

Ultrafast X-rays resolve the electron, proton, and solvent steps of proton-coupled electron transfer in water

Neuropixels probe fusing 960 recording sites with on-shank optogenetic light emitters

Mass spec measures fluctuation energies for 5,778 protein domains in parallel

Ancient-DNA time series reveal hundreds of alleles under directional selection in humans

Nine trillion base pairs of training, a megabase of context, single-nucleotide resolution.

A precise single-letter edit reawakens protective fetal hemoglobin without cutting DNA.

One model predicts thousands of regulatory genomic tracks and tops specialist tools on variant effects.

Single-cell multiomic profiling maps hippocampal neurogenesis across ageing and Alzheimer's disease

After a personalized neoantigen mRNA vaccine, 11 of 14 TNBC patients stayed relapse-free for up to six years

A generative model scaffolds enzyme active sites from functional-group positions alone, no residue order required.

Bimagrumab plus semaglutide produced greater weight loss than either drug alone in a phase 2 trial

A framework using Kolmogorov-Arnold networks to discover symbolic physical laws from data

A REG3A-to-KHSRP axonal loop brakes peripheral nerve regeneration through localized mRNA translation

A 4D-printed metamaterial absorber that reshapes on heating to retune its radar-band absorption

Five genomic factors explain most shared genetic risk across 14 psychiatric disorders

Pesticide residues rank as the second strongest driver of soil biodiversity across European soils

Electron-scattering line shapes cut estimated black-hole masses about a hundredfold.

A single-cell map of bone-innervating sensory neurons identifies FGF9 as a driver of fracture repair

Normal sleep raises plasma amyloid beta and tau versus sleep deprivation in a randomized crossover trial

Drug-loaded nanoparticles hijack skull immune cells to bypass the blood-brain barrier for stroke therapy

A generative model builds active metallohydrolases straight from chemistry, no lab tinkering required.

An RL agent writes machine-checkable Lean proofs for competition mathematics.

A GPT-style model forecasts more than 1,000 diseases decades ahead and generates synthetic health records.

A strongly binding phosphonic acid interlayer gives perovskite cells a T90 of nearly 3000 hours at 85°C

An AI model generates spatial proteomics from H&E slides to improve lung cancer prognostic accuracy

A multimodal whole-slide foundation model for pathology that works without fine-tuning

An open model develops self-reflection and verification with no human reasoning examples.

An open pipeline turns AlphaFold2 into nanomolar binders without high-throughput screening.

Adding two feedbacks that models usually ignore cuts the room left under 1.5 C by a quarter.

High-dimensional profiling reveals how a gene-edited pig organ is rejected, and how it holds.

Returned asteroid samples hold nucleobases, amino acids, and a first hint of tryptophan.

A subretinal photovoltaic implant plus infrared glasses gave most trial patients back central sight in a disease with no prior treatment.

A dedicated satellite resolves individual leaking sites across the planet's biggest fossil-fuel basins.

Gravitational-wave merger confirms horizon area grows and the remnant is Kerr

Imagined sentences are decoded in real time, and a mental password stops the device from listening in.

MoM-z14 at redshift 14.44 pushes the spectroscopic frontier of cosmic dawn.

Homogenizing chlorine in perovskite films yields 27.2% certified solar-cell efficiency

Second-order out-of-time-order correlators stay sensitive where scrambling usually erases the dynamics.

A two-level, language-guided policy autonomously completes the clip-and-cut phase of gallbladder removal and corrects its own mistakes.

A single AI beats operational forecasts for weather, air quality, ocean waves, and cyclones at a fraction of the compute.

An in vivo edit of the liver ANGPTL3 gene lowered triglycerides and LDL in a phase 1 trial.

A once-daily small-molecule drug cut body weight by double digits in a large phase 3 obesity trial.

A computational method builds small proteins programmed to recognize chosen DNA targets and control nearby genes.

A language model invented OpenCRISPR-1, a Cas9 hundreds of mutations from anything in nature.

Haplotype-resolved assemblies close most remaining gaps and fully sequence 1,246 centromeres.

One fine-tuned model forecasts human choices across 160 psychology experiments.

A six-atom, all-nitrogen allotrope isolated and kept stable at cryogenic temperatures.

Fresh Gaia and Hubble data turn our Galaxy's long-assumed merger into a coin toss.

A Chinese fusion device holds plasma densities up to 65% above a barrier long thought to trigger disruption.

An intracranial biomarker forecasts response to BNST-NAc stimulation for treatment-refractory depression.

The lightest planet ever seen in direct imaging, caught sculpting a gap in a young star's debris disc.

A targeted nanoparticle reprograms T cells into cancer fighters, skipping the factory.

Three years of galaxy maps favor an evolving dark energy over Einstein's constant.

A cobalt-nickel core wrapped in doped ceria breaks the usual trade-off between how efficiently and how long a high-temperature CO2 catalyst runs.

MICrONS fused live neural activity with a full wiring diagram of mouse visual cortex.

Long-term follow-up shows vaccine-induced T cells persist and track with delayed recurrence.

Generative AI builds serine hydrolases with efficiencies approaching natural proteins.

A single infusion of stem-cell-derived islets restored insulin independence in most recipients.

Integrated photonics generates GKP states, a key ingredient for fault-tolerant light-based quantum computing.

The first personalized in vivo base-editing medicine, from diagnosis to dosing in about six months.

A blinded trial pits a medical language model against 20 primary care doctors on text consultations.

A generative model proposes crystals meeting target properties, and one was synthesized and measured.

A foundation model for spreadsheets outperforms tuned gradient-boosted trees on small data.

Satellites reveal a reversal of a decades-long freshening trend that tracks the loss of Antarctic sea ice.

A mid-infrared spectrum points again at dimethyl sulfide, but still short of proof.

Precision tritium spectroscopy pushes the electron-antineutrino mass below half an electronvolt.

An interferometric parity measurement in InAs-Al nanowires, a building block a topological qubit would need.

A single carbon carrying four hydroxyl groups is synthesized in space-simulating ice for the first time.

One pretrained model predicts cortical responses to stimuli it never saw, and even reads out cell types and wiring.

Oxford teleports a logic gate between trapped-ion modules and runs Grover's search across the link.